Karen W. Gripp, MD is the Chief of the Division of Medical Genetics at the Nemours Childrens’ Hospital in Wilmington, DE. She is a Professor of Pediatrics at the S. Kimmel Medical College at T. Jefferson University. Dr. Gripp is board certified in pediatrics and medical genetics. She serves as the VP Clinical Genetics for the. At Nemours, Dr. Gripp serves as medical director for the Genetic Testing Stewardship Program and the Molecular Diagnostic Laboratory. On the board of the American College of Medical Genetics and Genomics Dr. Gripp serves as VP Clinical Genetics. Her clinical research focuses on Costello syndrome and other RASopathies, novel syndrome delineation and machine learning supported facial feature analysis. She has co-authored >180 peer reviewed publications. Her professional activities include participation in the ClinGen expert panels on RASopathies and on inherited cancer predisposition.