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Objectives

• Describe the typical disease course expected in pediatric patients with IgA vasculitis with nephritis.
• Identify potential clinical and histopathological risk factors for more aggressive disease and/or risk for continued disease activity over time.
• Define dysfunctional uterine bleeding and current clinical practice guidelines.
• Educate providers on dysfunctional uterine bleeding clinical pathway.
• Recognize common clinical features associated with DiGeorge Syndrome (22q11.2 deletion syndrome).
• Discuss associations between 22q11.2DS, autoimmunity, and psychosis spectrum disorders.
• Compare the variable clinical presentations of infective endocarditis in children, including potential complications.
• Acknowledge the clinical characteristics contributing to the pathogenesis of infective endocarditis in children.
• Be aware of potential predictors of noninvasive positive pressure ventilation (NIPPV) failure in patients with respiratory viral panel (RVP) positive bronchiolitis.
• Illustrate potential uses for Etiometry in clinical research.

Practice Change

• Increase prescription of IV iron and aygestin in emergency department for patients with dysfunctional uterine bleeding.
• Develop a higher degree of suspicion for infective endocarditis in patients with prolonged fever and potential pulmonary or systemic emboli.

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