ERLYN C. SMITH, M.D.
erlyn.smith@nemours.org

EMPLOYMENT
University of Florida Health Pediatric Subspecialties at Studer Family Children’s Hospital at Ascension Sacred
Heart Hospital
5151 North Ninth Avenue, Pensacola, FL 32504
August 2018 – Present
- Assistant Professor of Pediatrics
- Responsible for management of pediatric hematology and oncology patients in the inpatient and outpatient
settings with focus on solid tumors, sarcomas, Hodgkin Lymphoma, and acute myeloid leukemia.
- Responsible for bedside and didactic teaching of pediatric residents
- Career and research mentor for pediatric residents
- Site Principal Investigator of Children’s Oncology Group Clinical Trials, June 2021-Present
- Interprofessional Collaborative Practice Education Faculty Member for the Pediatric Tumor Board
- Member of the Pediatric Inpatient Committee
- Credentials Committee Member at Studer Family Children’s Hospital at Ascension
Sacred Heart
- Member of the Pediatric Residency Program Evaluation Committee
Banner Children’s Specialists Hematology/Oncology at Cardon Children’s Medical Center
1432 South Dobson Road Suite 107, Mesa, Arizona
July 2012 – July 2018
- Site Principal Investigator for Children’s Oncology Group Clinical Trials, 2017-2018.
- Clinical Assistant Professor of Child Health, University of Arizona College of Medicine, Phoenix
- Primary pediatric oncologist for 30+ patients with leukemia, lymphoma, sarcomas, and solid tumors
including those enrolled on COG clinical trials.
- Responsible for management of pediatric hematology and oncology patients in the inpatient and outpatient
settings.

EDUCATION
M.D., Rosalind Franklin University of Medicine and Science/The Chicago Medical School
3333 Green Bay Road, North Chicago, IL 60064-3095
July 2002 – June 2006
B.S., University of California, Los Angeles, Los Angeles, CA
Major: Neuroscience; September 1997 – June 2001
UCLA Undergraduate Admission
1147 Murphy Hall, Box 951436, Los Angeles, CA 90095-1436

GRADUATE MEDICAL EDUCATION
Pediatric Hematology/Oncology Fellowship Training at Children’s Hospital of Orange County
1201 W. La Veta Avenue, Orange CA, 92868
July 2009 – June 2012
Pediatric Residency Training at Children’s Hospital of Orange CountyDepartment of Pediatrics
333 The City Blvd. West, Suite 800, Orange, CA 92868-4482
July 2006 – June 2009
BOARD CERTIFICATION AND LICENSURE
American Board of Pediatrics – Active, 2021
American Board of Pediatrics, Subboard of Hematology and Oncology – Active, 2013
Florida Medical License – Active
DEA License – Active

PROFESSIONAL MEMBERSHIPS
American Society of Pediatric Hematology and Oncology
American Academy of Pediatrics
Florida Chapter, American Academy of Pediatrics
 

AWARDS & HONORS
▪ Physician of the Month – February 2018
▪ World of Difference Award from Cardon Children’s Hospital 2017
▪ Member of Alpha Omega Alpha Honor Medical Society: 2006
▪ Graduated Cum Laude: UCLA, June 2001

LEADERSHIP EXPERIENCE
Professional: Principal Investigator of COG Clinical Trials at Cardon Children’s Medical Center, 2017-2018
Co-Chair of Pediatric Hematology/Oncology Quality and Safety Committee, 2012-2018
Principal Investigator of COG Clinical Trials at Studer Family Children’s Hospital at Ascension
Sacred Heart, June 2021 - Present
Medical Director of Pediatric Oncology Research, September 2023 - Present
Fellowship: Chief Fellow Physician for Children’s Hospital of Orange County Pediatric
Hematology/Oncology Fellowship Program, July 2011 – June 2012
Residency: Class Representative of Graduate Medical Education Committee, 2006-2009
Medical School: Vice President of American Medical Women’s Association 2003-2004
Executive Board Member of Pediatrics Interest Group 2003-2004
Executive Board Member of CMS American Medical Student Association 2003-2004

RESEARCH EXPERIENCE
University of Florida Health Pediatric Subspecialties at Studer Family Children’s Hospital at Ascension Sacred
Heart Hospital
 Site Principal Investigator of Children’s Oncology Group Clinical Trials, June 2021 – Present
 Medical Director of Pediatric Oncology Research, September 2023 - Present
Banner Children’s Specialists Hematology/Oncology at Cardon Children’s Medical Center
 Site Principal Investigator of Children’s Oncology Group Clinical Trials, 2017-2018
University of California, Irvine, School of Medicine, Department of Epidemiology
Fellow Research Project: July 2010 – June 2012
● Delay in surgical treatment after breast cancer diagnosis in young women by race and ethnicity
o Published in JAMA Surgery, June 2013
● Association between insurance and socioeconomic status and risk of advanced stage Hodgkin lymphoma in
adolescents and young adults
o Published in Journal of Cancer, June 2012
● Seasonal Variation in the Diagnosis of Hodgkin’s Lymphoma in Young Adults
o Abstract presented as American Society of Pediatric Hematology/Oncology Meeting April 2011
American Pediatric Society and Society for Pediatric Research
Student Researcher at Children’s Memorial Hospital (Chicago, IL); June – August 2003
▪ Designed a parent survey that could assess physical activity in children ages 2-10 years
▪ Abstract was presented at 2004 Annual Pediatric Academic Societies Meeting
UCLA & West Los Angeles Veterans Affairs Psychiatry & Behavioral Sciences
Clinical Research Assistant I; employed July 2001 - July 2002
▪ Processing of PET and MRI images for research on smoking cessation and obsessive-compulsive disorder
Erlyn Smith, MD
UCLA Department of Molecular and Medical Pharmacology
Student Researcher; April 2000 – June 2001
▪ Investigated the neuroanatomical and neurochemical abnormalities in non-human primates with impulsive
aggressive behavior
UCLA Department of Neurology, Stroke Study
Clinical Research Assistant; volunteered April 1999 – April 2000
▪ Investigated the safety and efficacy of experimental drugs and procedures for acute ischemic stroke
Life Sciences Summer Undergraduate Research Program, University of Minnesota, Minneapolis
Student Researcher; June 1999 – August 1999
▪ Investigated the differentiation of human stem cells in vitro.

PUBLICATIONS
1. Abdul Hadi T, Ananthasivan S, Andrucioli A, Smith EC. Vitamin B12 deficiency disguised as hemolytic
anemia: a case presentation. Cureus 16(1): e51815. doi:10.7759/cureus.51815.
2. Agarwal P, Burns JJ, Gao H, Smith EC. Improved Management of Sickle Cell Pain Crisis in Pediatric
Emergency Department through Use of Intranasal Fentanyl: A Quality Improvement Project. European Society
of Medicine (in press).
3. Smith E, Montilla A, Krishnan C. Is it a teratoma? Is it a nephroblastoma? No, it is a teratoma with
nephroblastoma: a rare tumor in pediatric oncology. International Journal of Contemporary Pediatrics. 2023
Nov; 10(11):1716-1720.
4. Smith E, Krishnan C. An unusual presentation of a pediatric patient with mixed phenotype acute leukemia with
PICALM-MLLT10 gene rearrangement. Pediatric Hematology and Oncology. Published online 12 May 2023;
1-8.
5. Agarwal P, Balkaransingh P, Krishnan C, Smith E. Acute Lymphoblastic leukemia after COVID-19 infection:
a coincidence or a second hit. International Journal of Contemporary Pediatrics. 2023 Mar; 10 (3):365-368.
6. Smith E, Reddivalla N. Tailored therapy and bloodless supportive care measures for a Jehovah’s witness with
metastatic Ewing sarcoma. International Journal of Contemporary Pediatrics. 2023 Feb; 10(2):241-244.
7. Schwartz JH, Smith E. Prenatal Presentation of an adrenocortical tumor. Cancer Reports; 5(10): e1670.
8. Amit ML, Barr L, Smith E. Benign Cyst or Malignancy? A six-year-old with primitive small round cell
sarcoma of the right buttock: a case report. International Journal of Contemporary Pediatrics. 2022 Feb;
9(2):192-195.
9. Smith EC, Ziogas A, Anton-Culver H. Delay in surgical treatment after breast cancer diagnosis in young
women by race and ethnicity. JAMA Surgery; 2013 Jun 1;148(6):516-23.
10. Smith EC, Ziogas A, Anton-Culver H. Association between insurance and socioeconomic status and risk
of advanced stage Hodgkin lymphoma in adolescents and young adults. Cancer; 2012 Dec 15;118(24):6179-87.
11. Brody AL, Mandelkern MA, Lee GS, Smith EC, Sadeghi M, Saxena S, Jarvik ME, & London ED.
Attenuated cue-induced craving and anterior cingulate cortex activation in bupropion-treated smokers.
Psychiatry Research: Neuroimaging 130 (2004) 269-281.
12. Brody AL, Mandelkern MA, Jarvik ME, Lee GS, Smith EC, Huang JC, Bota RG, Bartzokis G, London ED.
Differences between Smokers and Nonsmokers in Regional Gray Matter Volume and Densities. Biological
Psychiatry 2004; 55: 77-84.
13. Saxena S, Brody AL, Maidment KM, Smith EC, Zohrabi N, Katz E, Baker SK, Baxter LR. Cerebral Glucose
Metabolism in Obsessive-Compulsive Hoarding. Am J Psychiatry 2004; 161:1038-1048.
ABSTRACTS
1. Pallavi Agarwal, James Joseph Burns, Erlyn Smith. Improvement in the management of Vaso-occlusive crisis
in Pediatric Emergency Department through early use of Intranasal Fentanyl: A Quality Improvement Project.
Studer Family Children’s Hospital at Ascension Sacred Heart; University of Florida, Department of Pediatrics.
Pediatric Residency Research Poster Presentation 2023.
2. Khushi Bhattarai, Erlyn Smith. Approach to non-neutropenic fever in well-appearing pediatric oncology patients.
Studer Family Children’s Hospital at Ascension Sacred Heart; University of Florida, Department of Pediatrics.
Pediatric Residency Research Poster Presentation 2023
Erlyn Smith, MD
3. Jiasen He, James Burns, Aashima Pandhi, Erlyn Smith. Vaccination Coverage Among Children with Sickle Cell
Disease. Studer Family Children’s Hospital at Ascension Sacred Heart; University of Florida, Department of
Pediatrics. Southern Regional Meeting 2021.
4. Erlyn C. Smith, Argyrios Ziogas, Hoda Anton-Culver. Children’s Hospital of Orange County; University of
California, Irvine, Department of Epidemiology; Genetic Epidemiology Research Institute, University of
California, Irvine; Chao Family Comprehensive Cancer Center, University of California, Irvine. Seasonal
Variation in the Diagnosis of Hodgkin’s Lymphoma in Young Adults. American Society of Pediatric
Hematology/Oncology Meeting April 2011
5. Robert S. Greenberg, Erlyn Smith, Adolfo J. Ariza, Susan A. LeBailly, Helen J. Binns. Mary Ann and J Milburn
Smith Child Health Research Program, Children s Memorial Hospital; Feinberg School of Medicine,
Northwestern University, Chicago, IL. Developing a Pictographic Child Activity Questionnaire A New Tool
To Assess the Physical Activity of Young Children. 2004 Annual Pediatric Academic Societies Meeting.

LECTURES
1. Pediatric Grand Rounds. “Neutropenia in Pediatrics.” Studer Family Children’s Hospital. November 2021.
2. Pediatric Grand Rounds. “Relapse Acute Lymphoblastic Leukemia and CAR-T cell Therapy.” Studer Family
Children’s Hospital. November 2020.
3. Pediatric Grand Rounds. “Immune Thrombocytopenia, Something Old and Something New.” Studer Family
Children’s Hospital. August 2019.
4. “Venous Thromboembolism in Children.” East Valley Pediatric Society Lecture Series. Mesa, Arizona. August
2014.
5. “Death and Dying.” Camp Sunrise Fundraising Event Guest Speaker. Scottsdale, Arizona. February 2014.